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Structural features of the mRNAs that are most upregulated.
| Description | P value | ||
|---|---|---|---|
| shorter 5′-UTR | t test | *** | 2.805E-08 |
| higher 5′-UTR MFE | t test | *** | 1.558E-11 |
| fewer uORF | χ2 | *** | 1.096E-07 |
| TISU elements | χ2 | *** | 6.074E-06 |
| TOP/TOP like | χ2 | ns | |
| AU-rich elements | χ2 | ns |
These included upstream open-reading frame (uORF) = 833; terminal oligopyrimidine tract TOP/TOP-like = 126; AU-rich elements = 297; translation initiator of short 5′-UTR, TISU = 28 MFE = minimum-free energy.
