Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 13;11:16478. doi: 10.1038/s41598-021-94769-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

A soft-robotic constrictor for dynamic compressive mechanical loading of living tissue. (a) Circumferential tissue compression occurs during the constriction of tubular organs such as blood vessels and airways. (b) Normally coiled soft robotic cell culture platform and its pneumatically driven unrolling motion. Scale bar, 5 mm. (c) Fabrication of the soft robotic device through irreversible bonding of a thin stretched PDMS strip to a microchannel-containing PDMS slab (Steps 1, 2, and 3) and subsequent release of the bonded assembly (Step 4). (d,e) Sequential steps for establishing cell culture on the microengineered device. Red arrows labeled “ON” at the bottom of schematics represent application of pneumatic pressure to the microchannels. (f) Compression of cultured tissue layer through removal of air pressure from the microchannels (shown with a blue arrow labeled “OFF”) and the resultant bending of the culture substrate.