Table 3.
Wilcoxon signed rank test for pairwise comparison of performance obtained by ST, SB, and SeqSNR on the full and reduced feature sets.
| Task | Feature Set | Pairwise Comparison | P Value for AUPRC | P Value for AUROC |
|---|---|---|---|---|
| AKI | Full | ST vs SB | <.001 | <.001 |
| SeqSNR vs SB | <.001 | <.001 | ||
| SeqSNR vs ST | .002 | <.001 | ||
| Reduced | ST vs SB | <.001 | <.001 | |
| SeqSNR vs SB | <.001 | <.001 | ||
| SeqSNR vs ST | .635 | .060 | ||
| CRRT dialysis | Full | ST vs SB | .003 | <.001 |
| SeqSNR vs SB | .035 | .739 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| Reduced | ST vs SB | <.001 | .019 | |
| SeqSNR vs SB | .002 | .679 | ||
| SeqSNR vs ST | <.001 | .063 | ||
| Vasoactive medications | Full | ST vs SB | <.001 | <.001 |
| SeqSNR vs SB | <.001 | .888 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| Reduced | ST vs SB | .020 | <.001 | |
| SeqSNR vs SB | <.001 | <.001 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| First MV | Full | ST vs SB | .330 | <.001 |
| SeqSNR vs SB | <.001 | .006 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| Reduced | ST vs SB | .149 | .005 | |
| SeqSNR vs SB | <.001 | .011 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| Mortality | Full | ST vs SB | .081 | <.001 |
| SeqSNR vs SB | .019 | <.001 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| Reduced | ST vs SB | <.001 | <.001 | |
| SeqSNR vs SB | .203 | <.001 | ||
| SeqSNR vs ST | <.001 | <.001 | ||
| Remaining LoS | Full | ST vs SB | .021 | <.001 |
| SeqSNR vs SB | .271 | .021 | ||
| SeqSNR vs ST | .025 | <.001 | ||
| Reduced | ST vs SB | <.001 | .186 | |
| SeqSNR vs SB | <.001 | <.001 | ||
| SeqSNR vs ST | <.001 | <.001 |
To adjust for multiple hypothesis testing, we perform false discovery rate correction considering all experiments performed in this study and report the false discovery rate–adjusted P values. The P values marked in bold are statistically significant on the 95% confidence limit (α = 0.05).
AKI: acute kidney injury; AUPRC: area under the precision-recall curve; AUROC: area under the receiver-operating characteristic curve; CRRT: continuous renal replacement therapy; LoS: length of stay; MV: mechanical ventilation; SB: shared bottom; SeqSNR: sequential subnetwork routing; ST: single task.