Fig. 4.

Distribution of node betweenness centrality. a Betweenness centrality of unique positive connections in opioid-exposed group b Betweenness centrality of unique positive connections in controls c Distribution of betweenness centrality of overlapping connections seen in both groups d List of regions with the highest betweenness centrality unique to the opioid-exposed group e List of regions with the highest betweenness centrality unique to controls f List of regions with the highest betweenness centrality seen in both groups.