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. 2021 Jun 1;7(5):507–516. doi: 10.1002/cjp2.225

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© 2021 The Authors. The Journal of Pathology: Clinical Research published by The Pathological Society of Great Britain and Ireland & John Wiley & Sons, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Representative micrographs of MCN‐AICs showing invasion of varying sizes and depths. (A) A carcinoma focus located within ovarian‐type stroma and minimal in size (less than 0.1 cm) (case 1). (B) Extensive invasion with the greatest dimension of 3 cm (case 3). Although large in size, the invasive component was restricted to ovarian‐type stroma and cyst septa. (C) A 0.3 cm carcinoma focus embedded in the superficial acellular hyalinized capsular stroma, while the outer layer of the cyst remains clear (case 8). (D) Invasive component infiltrating throughout the whole cyst wall (case 13), presumably arising from the mural nodule (left) and spreading into the fibrotic capsule (central) with no perineural and vascular involvement (right). (E) Invasive carcinoma intruding into the surrounding pancreatic parenchyma (case 14). (F) Extensive invasion with carcinoma penetrating through the intestinal wall to the epithelial surface (case 15). Hematoxylin and eosin stain.