Table 3.
Counts of CD3, CD4, CD8, CD45, and FOXP3 TIL subtypes by molecular subtype (n = 282).
| Luminal A | Luminal B | HER2 type | Triple negative | |||
|---|---|---|---|---|---|---|
| HER2− | HER2+ | |||||
| n (%) | n (%) | n (%) | n (%) | n (%) | P value | |
| Total | 145 (51) | 89 (32) | 18 (6) | 9 (4) | 21 (7) | |
| CD3 | ||||||
| High | 29 (20) | 19 (21) | 6 (33) | 5 (56) | 10 (48) | 0.009 |
| Low | 116 (80) | 70 (79) | 12 (67) | 4 (44) | 11 (52) | |
| CD4 | ||||||
| High | 32 (22) | 24 (27) | 6 (33) | 1 (11) | 7 (33) | 0.52 |
| Low | 113 (78) | 65 (73) | 12 (67) | 8 (89) | 14 (67) | |
| CD8 | ||||||
| High | 28 (19) | 20 (23) | 6 (33) | 5 (56) | 11 (52) | 0.002 |
| Low | 117 (81) | 69 (77) | 12 (67) | 4 (44) | 10 (48) | |
| CD45 | ||||||
| High | 27 (19) | 22 (25) | 8 (44) | 4 (44) | 9 (43) | 0.016 |
| Low | 118 (81) | 67 (75) | 10 (56) | 5 (56) | 12 (57) | |
| FOXP3 | ||||||
| High | 24 (17) | 19 (21) | 9 (50) | 6 (67) | 12 (57) | <0.001 |
| Low | 121 (83) | 70 (79) | 9 (50) | 3 (33) | 9 (43) | |
Number of cases (n) and % within molecular subtypes are given according to the St Gallen consensus criteria 2013 [23]. P values were obtained using Pearson's chi‐square test. High CD3, CD4, CD8, CD45, and FOXP3 counts are given by the upper quartile.