Table 3.
Characteristics of the subjects in relation to the image category at follow-up
| Parameter | “Atrophy” | “Normal” | “iNPH” | Number of subjects |
|---|---|---|---|---|
| Total (n) | 42 | 63 | 8 | 113 |
| Age (years, mean ± SD) | 74 ± 7 | 67 ± 10 | 77 ± 5 | 113 |
| Sex (female/male, n) | 19/23 | 32/31 | 7/1 | 113 |
| Education (score, mean ± SD)a | 2.5 ± 1.0 | 2.5 ± 1.0 | 2.0 ± 1.1 | 113 |
| Alcohol (daily units, mean ± SD) | 1.1 ± 1.0 | 0.8 ± 0.8 | 0.7 ± 0.8 | 107 |
| Diabetes (y/n, n) | 5/36 | 4/57 | 1/6 | 109 |
| Hypertension (y/n, n) | 19/22 | 33/29 | 4/3 | 110 |
| Hypercholesterolaemia (y/n, n) | 26/15 | 43/19 | 6/1 | 110 |
| WMH (Fazekas score, mean ± SD) | 2.5 ± 1.5 | 1.8 ± 1.1 | 3.8 ± 1.6 | 113 |
| SPPB (score, mean ± SD)b | 3.6 ± 0.7 | 3.8 ± 0.4 | 3.3 ± 1.0 | 99 |
| TMT-B (sec, mean ± SD) | 139 ± 75 | 110 ± 48 | 194 ± 53 | 109 |
| Walking speed (m/s, mean ± SD) | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 | 108 |
| Executive function (z-score, mean ± SD) | − 0.0 ± 0.7 | 0.2 ± 0.6 | − 0.5 ± 0.5 | 74 |
| g-factor (z-score, mean ± SD) | − 0.3 ± 1.1 | 0.3 ± 0.9 | − 0.8 ± 0.8 | 72 |
| Memory (z-score, mean ± SD) | − 0.2 ± 1.1 | 0.2 ± 0.9 | − 1.1 ± 0.7 | 103 |
| Visuopractical Skills (z-score, mean ± SD) | − 0.3 ± 0.8 | 0.3 ± 0.8 | − 0.6 ± 1.2 | 107 |
iNPH: idiopathic normal pressure hydrocephalus-associated imaging findings; SD: standard deviation; WMH: white matter hyperintensities; SPPB: short physical performance balance; TMT-B: Trail Making Test B
arange of education score: 1 (homemaker, farmer)—4 (academic career)
brange of SPPB score: 1–4