Table 4.
Differences of the study parameters between the imaging categories at follow-up
| Parameter | Overalla | “atrophy” vs. “normal”b | “atrophy” vs. “iNPH”b | “iNPH” vs. “normal”b |
|---|---|---|---|---|
| Age (years) | < 0.0001* | 0.0002* | NS | 0.0205* |
| Sex (n) | NS | NS | 0.0283* | 0.0494* |
| Education (score) | NS | NS | NS | NS |
| Alcohol (daily units) | NS | NS | NS | NS |
| Diabetes (n) | NS | NS | NS | NS |
| Hypertension (n) | NS | NS | NS | NS |
| Hypercholesterolaemia (n) | NS | NS | NS | NS |
| WMH (Fazekas score) | 0.0009* | 0.0470* | NS | 0.0027* |
| SPPB (score) | NS | NS | NS | NS |
| TMT-B (sec) | 0.0020* | NS | NS | 0.0036* |
| Walking speed (m/s) | NS | NS | NS | NS |
| Executive function (z-score) | 0.0129* | NS | NS | 0.0210* |
| g-factor (z-score) | 0.0318* | NS | NS | NS |
| Memory (z-score) | 0.0068* | NS | NS | 0.0155* |
| Visuopractical Skills (z-score) | 0.0015* | 0.0043* | NS | NS |
iNPH idiopathic normal pressure hydrocephalus-associated imaging findings, WMH white matter hyperintensities, SPPB short physical performance balance, TMT-B Trail Making Test B
aKruskal–Wallis test in continuous parameters, Fisher’s exact test or Chi-Squared test in the remaining parameters
bDunn’s test in continuous parameters, Chi-Squared test in the remaining parameters
*significant difference