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. 2021 Aug 14;18:37. doi: 10.1186/s12987-021-00268-x

Table 4.

Differences of the study parameters between the imaging categories at follow-up

Parameter Overalla “atrophy” vs. “normal”b “atrophy” vs. “iNPH”b “iNPH” vs. “normal”b
Age (years)  < 0.0001* 0.0002* NS 0.0205*
Sex (n) NS NS 0.0283* 0.0494*
Education (score) NS NS NS NS
Alcohol (daily units) NS NS NS NS
Diabetes (n) NS NS NS NS
Hypertension (n) NS NS NS NS
Hypercholesterolaemia (n) NS NS NS NS
WMH (Fazekas score) 0.0009* 0.0470* NS 0.0027*
SPPB (score) NS NS NS NS
TMT-B (sec) 0.0020* NS NS 0.0036*
Walking speed (m/s) NS NS NS NS
Executive function (z-score) 0.0129* NS NS 0.0210*
g-factor (z-score) 0.0318* NS NS NS
Memory (z-score) 0.0068* NS NS 0.0155*
Visuopractical Skills (z-score) 0.0015* 0.0043* NS NS

iNPH idiopathic normal pressure hydrocephalus-associated imaging findings, WMH white matter hyperintensities, SPPB short physical performance balance, TMT-B Trail Making Test B

aKruskal–Wallis test in continuous parameters, Fisher’s exact test or Chi-Squared test in the remaining parameters

bDunn’s test in continuous parameters, Chi-Squared test in the remaining parameters

*significant difference