Table 2.
Univariable and multivariable analysis of TST and IGRA positivity
| IGRA positivity (≥ 8 spots) | TST(≥ 10 mm) | |||||
|---|---|---|---|---|---|---|
| n/N (%) | p for X2 test# | Adjusted OR*(95%CI) | n/N (%) | p for X2 test# | Adjusted OR*(95%CI) | |
| Sex | 0.32 | 0.98 | ||||
| Male | 35/3748 (0.9%) | Reference | 115/3748 (3.1%) | Reference | ||
| Female | 17/2454 (0.7%) | 0.7 (0.4–1.2) | 76/2454 (3.1%) | 1.0 (0.8–1.3) | ||
| Age(years) | 0.006 | 0.049 | ||||
| 0–2 y | 12/2327 (0.5%) | Reference* | 63/2327 (2.7%) | Reference* | ||
| 3–4 y | 4/924 (0.4%) | 0.8 (0.3–2.2)* | 21/924 (2.3%) | 0.8 (0.5–1.2) | ||
| 5–18 | 36/2951 (1.2%) | 2.5 (1.4–4.4)* | 107/2951 (3.6%) | 1.3 (1.1–1.8)* | ||
| District | < 0.001 | < 0.001 | ||||
| Eastern | 28/4662 (0.6%) | Reference* | 109/4662 (2.3%) | Reference* | ||
| Middle | 10/1042 (1.0%) | 2.1 (1.1–3.7)* | 44/1042 (4.2%) | 2.0 (1.5–2.6)* | ||
| Western | 14/498 (2.8%) | 3.2 (1.7–6.1)* | 38/498 (7.6%) | 3.2 (2.4–4.4)* | ||
| Resident place | 0.78 | 0.82 | ||||
| City | 27/3376 (0.8%) | Reference | 105/3376 (3.1%) | Reference | ||
| Rural | 25/2826 (0.9%) | 1.5 (0.9–2.6) | 86/2826 (3.0%) | 1.0 (0.8–1.3) | ||
| BCG vaccination history | 0.98 | 0.07 | ||||
| Yes | 51/6086 (0.8%) | – | 186/6086 (3.1%) | Reference | ||
| No | 1/116 (0.9%) | – | 5/116 (4.3%) | 1.2 (0.7–2.1) | ||
| Presence of BCG scar | 0.79 | 0.77 | ||||
| Yes | 49/5895 (0.8%) | Reference | 183/5895 (3.1%) | Reference | ||
| No | 3/307 (1.0%) | 2.0 (0.8–5.0) | 8/307 (2.6%) | 0.9 (0.5–1.6) | ||
| Exposure level | < 0.001 | < 0.001 | ||||
| No reported contact risk | 41/5833 (0.7%) | Reference* | 151/5833 (2.6%) | Reference* | ||
| Non-household contact risk | 6/274 (2.2%) | 1.5 (0.6–3.6)* | 23/274 (8.4%) | 2.7 (1.9–3.9)* | ||
| Household contact risk | 5/95 (5.3%) | 6.1 (2.7–13.9)* | 17/95 (17.9%) | 6.9 (4.5–10.7)* | ||
Data are n/N (%),unless otherwise indicated. n/N (%) is number positive /number with test results (proportion positive)
BCG Bacille Calmette Guerin, IGRA interferon-gamma release assay, TST tuberculin skin test, OR odd ratio, CI confidence interval
#: Univariable analysis; *: multivariable analysis, controlling for variables with p < 0.05 in univariable analysis. p values from the multivariable analysis for IGRA positivity was 0.02,0.005, 0.001 for age, district and exposure level respectively, for TST positivity was 0.13, < 0.001, < 0.001 for age, district and exposure level respectively