Table 4.
Association between KDM2A protein expression and clinical features in ccRCC
| Parameters | n | KDM2A mRNA expression in ccRCC | P | |
|---|---|---|---|---|
| Low, n (%) | High, n (%) | |||
| Gender | ||||
| Male | 29 | 1 (3.4%) | 28 (96.6%) | 0.181 |
| Female | 21 | 4 (19.0%) | 17 (81.0%) | |
| Age, years | ||||
| < 60 | 28 | 3 (10.7%) | 25 (89.3%) | 1.000 |
| ≥ 60 | 22 | 2 (9.1%) | 20 (90.9%) | |
| Location | ||||
| Left | 22 | 2 (9.1%) | 20 (90.9%) | 1.000 |
| Right | 28 | 3 (10.7%) | 25 (89.3%) | |
| BMI (kg/m2) | ||||
| < 24 | 20 | 0 (0%) | 20 (100%) | 0.149 |
| ≥ 24 | 30 | 5 (16.7%) | 25 (83.3%) | |
| Tumor size (cm) | ||||
| ≤ 7 | 35 | 5 (14.3%) | 30 (85.7%) | 0.304 |
| > 7 | 15 | 0 (0%) | 15 (100%) | |
| Smoking | ||||
| No | 39 | 5 (12.8%) | 34 (87.2%) | 0.495 |
| Yes | 11 | 0 (0%) | 11 (100%) | |
| Thrombus of renal vein | ||||
| No | 46 | 5 (10.9%) | 41 (89.1%) | 1.000 |
| Yes | 4 | 0 (0%) | 4 (100%) | |
| TNM stage | ||||
| T1–T2 | 38 | 5 (13.2%) | 33 (86.8%) | 0.440 |
| T3–T4 | 12 | 0 (0%) | 12 (100%) | |
| ISUP grade | ||||
| 1–2 | 35 | 4 (11.4%) | 31 (88.6%) | 1.000 |
| 3–4 | 15 | 1 (6.7%) | 14 (93.3%) | |
| Symptoms | ||||
| No | 32 | 4 (12.5%) | 28 (87.5%) | 0.768 |
| Yes | 18 | 1 (5.6%) | 17 (94.4%) | |
| Hypertension | ||||
| No | 29 | 4 (13.8%) | 25 (86.2%) | 0.567 |
| Yes | 21 | 1 (4.8%) | 20 (95.2%) | |