Skip to main content
. 2021 Aug 13;22:689. doi: 10.1186/s12891-021-04578-x

Table 2.

The Diagnostic Value of Inflammatory and Fibrinolytic Markers

Markers AUC Optimal cutoff Youden index SEN (%) SPE (%) PPV (%) NPV (%) +LR -LR
CRP (mg/L) 0.893 >8.8 0.7735 82.61 94.74 90.5 90.0 15.70 0.18
ESR (mm/h) 0.953 >34.0 0.7669 81.82 94.87 90.0 90.2 15.95 0.19
D-dimer (mg/L) 0.717 >1.7 0.4013 47.83 92.31 78.6 75.0 6.22 0.57
K (min) 0.800 <1.3 0.5362 86.96 66.67 60.6 89.7 2.61 0.20
Angle(°) 0.803 >70.7 0.5619 86.96 69.23 62.5 90.0 2.83 0.19
MA (mm) 0.895 >68.1 0.8004 82.61 97.44 95.0 90.5 32.22 0.18
A30(mm) 0.893 >66.5 0.7492 82.61 92.31 86.4 90.0 10.74 0.19
TPI(/sec) 0.867 >84.4 0.7057 78.26 92.31 85.7 87.8 10.17 0.24

AUC area under the curve, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio, CRP C-reactive protein, ESR erythrocyte sedimentation rate, K clotting time, Angle α-angle, MA maximum amplitude, A30 amplitude at 30 min, TPI thrombodynamic potential index