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. 2021 Aug 13;22:689. doi: 10.1186/s12891-021-04578-x

Table 3.

The Diagnostic Value of Combined Inflammatory and Fibrinolytic Markers

Markers AUC SEN (%) SPE (%) PPV (%) NPV (%) +LR -LR
CRP + ESR 0.980 100.00 89.47 84.6 100.0 9.50 0.000
CRP + K 0.943 91.30 94.74 91.3 94.7 17.35 0.092
CRP + Angle 0.946 91.30 94.74 91.3 94.7 17.35 0.092
CRP + MA 0.995 100.00 94.74 92.0 100.0 19.00 0.000
CRP + A30 0.999 100.00 97.37 95.8 100.0 38.00 0.000
CRP + TPI 0.968 91.30 97.37 95.5 94.9 34.70 0.089
ESR + K 0.958 86.36 94.87 90.5 92.5 16.84 0.140
ESR + Angle 0.953 86.36 94.87 90.5 92.5 16.84 0.140
ESR + MA 0.948 90.91 89.74 83.3 94.6 8.86 0.100
ESR + A30 0.948 81.82 97.44 94.7 90.5 31.91 0.190
ESR + TPI 0.955 81.82 97.44 94.7 90.5 31.91 0.190

AUC area under the curve, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio, CRP C-reactive protein, K clotting time, Angle α-angle, MA maximum amplitude, A30 amplitude at 30 min, TPI thrombodynamic potential index, ESR erythrocyte sedimentation rate