Table 3.
Peak (vs nadir) laboratory abnormalities identified among pregnant patients with SARS-CoV-2 infection stratified by the presence or absence of symptoms
| Variable | n | Asymptomatic | n | Symptomatic | P value | OR (95% CI) | Adjusted OR (95% CI) |
|---|---|---|---|---|---|---|---|
| Neutrophilia Neutropenia Lymphocytosis LymphopeniaLeukocytosis |
42 42 42 4261 |
28 (66.7) 1 (2.4) 1 (2.4) 27 (64.3) 34 (67.1) |
56 56 56 56 67 |
45 (80.4) 3 (5.4) 2 (3.6) 42 (75.0) 18 (26.9) |
.12 .42 .62 .25 .02 |
2.05 (0.82–5.13) 2.32 (0.23–23.14) 1.48 (0.13–16.91) 1.67 (0.70–3.99) 0.41 (0.20–0.84) |
— — — — 0.48 (0.19–1.18) |
| Leukopenia | 61 | 0 (0) | 67 | 7 (10.4) | .01 | 8.42 (1.01–70.6) | 4.97 (0.37–66.65) |
| Elevated ferritin level | 27 | 1 (3.7) | 40 | 2 (5.0) | .65 | 1.37 (0.12–15.89) | — |
| Transaminitis | 50 | 6 (11.8) | 53 | 12 (21.8) | .16 | 2.15 (0.74–6.25) | — |
| Elevated hsCRP level | 30 | 17 (56.7) | 42 | 34 (81.0) | .03 | 3.25 (1.13–9.34) | 4.51 (1.11–18.40) |
| Elevated D-dimer level | 37 | 37 (100.0) | 47 | 45 (95.7) | .20 | 0.63 (0.05–7.17) | — |
| Elevated PCT level | 38 | 17 (44.7) | 47 | 25 (53.2) | .44 | 1.40 (0.59–3.31) | — |
| Elevated LDH level | 47 | 10 (21.3) | 47 | 12 (25.5) | .63 | 1.27 (0.49–3.31) | — |
Data are presented as number (percentage), unless otherwise indicated.
Adjusted ORs are adjusted for gestational age.
CI, confidence interval; hsCRP, high-sensitivity C-reactive protein; LDH, lactate dehydrogenase; OR, odds ratio; PCT, procalcitonin.
Fisher. Laboratory analysis of SARS-CoV-2 in pregnant patients. Am J Obstet Gynecol MFM 2021.