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. Author manuscript; available in PMC: 2021 Aug 14.
Published in final edited form as: Curr Opin Cell Biol. 2020 Dec 9;70:18–26. doi: 10.1016/j.ceb.2020.11.002

Figure 1. Models for enhancer–promoter (E–P) interactions:

Figure 1

(a) Stable contact or stable loop model. (b) Dynamic contact model (hit-and-run). (c) Stable condensate model. (d) Dynamic condensate model (hit-and-run or dynamic kissing). Black arrow at the gene indicates active transcription.