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. 2021 Jun 16;18(14):3050–3058. doi: 10.7150/ijms.45980

Figure 2.

Figure 2

Levels of serum amylase, plasma endotoxin, and Evans blue were significantly increased, and those levels were markedly decreased in the SAP + Zn group compared to those in the SAP group. Levels of serum amylase in SAP + Zn group were significantly decreased compared to those in the 12 h and 24 h SAP group (a). Levels of plasma endotoxin in the SAP + Zn group were significantly decreased compared to those in the 24 h SAP group (b). Levels of Evans blue content in SAP + Zn group were significantly decreased compared to those in the 12 h and 24 h SAP groups (c). Levels of serum Zn levels in the SAP group were significantly decreased compared to those in the SS group and in the 6 h, 12 h, and 24 h SAP groups. However, the levels in the SAP + Zn group were increased compared to those in the SAP group (d). Levels of serum TNF-α and IL-1β in the SAP group were significantly increased compared to those in the SS group and SS + Zn group, and in the 6 h, 12 h, and 24 h SAP groups. However, the levels in the SAP + Zn group decreased significantly compared to those in the SAP group (e, f). The intercellular space was found to be widened in the SAP group (h) compared to the SS group (g), as observed by transmission electron microscopy. However, the injury was less severe in the SAP + Zn group (i) than in the SAP group. The data are expressed as means ± SD, *p < 0.05 and **p < 0.01.