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. 2021 Jul 23;18(14):3299–3308. doi: 10.7150/ijms.62530

Figure 5.

Figure 5

Changes in melanin index following product application for eight consecutive weeks. Twenty-two female patients with skin hyperpigmentation aged 37 to 55 participated in the study. The melanin index was analyzed at 2, 4, and 8 weeks after applying the test cream (Test groups) containing 68.6% AYC-P-E, and the control cream (Control groups) not containing AYC-P-E. Data from one of two independent experiments are shown. Data represent the mean ± standard error of measurement (SEM). *P<0.05 compared to the melanin index before application (0 week) of the test cream containing AYC-P-E; #P<0.05 compared to the melanin index before application (0 week) of the control cream not containing AYC-P-E; †P<0.05 comparison of the melanin index of the test and control groups at 2, 4, and 8 weeks.