Skip to main content
. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Trends Pharmacol Sci. 2021 Jul 23;42(9):789–801. doi: 10.1016/j.tips.2021.06.004

Figure 2. Memory NK cells and involvement of NK cells in vaccine recall responses.

Figure 2.

Vaccine- or infection-elicited inflammatory cytokines and viral products can promote expansion, differentiation and persistence of memory or adaptive NK cells with heightened effector function relative to their naive counterparts. During recall responses, vaccine-elicited memory T cells promote elevated NK-cell functionality via IL-2 while memory B cell-derived antibodies can promote killing of target cells via engagement of Fc receptor on NK cells (ADCC). Some memory NK cells are highly adept at antibody-dependent effector functions.