Table 3.
Correlations between TLR2, TLR4 and FXR expression and oesophagitis
| Basal TLR2 | Superficial TLR2 | Total TLR2 | Basal TLR4 | Superficial TLR4 | Total TLR4 | FXR | Macroscopic oesophagitis | |
|---|---|---|---|---|---|---|---|---|
| Histological oesophagitis | 0.45 (<0.01) | 0.34 (<0.01) | 0.48 (<0.01) | −0.04 (0.76) | −0.11 (0.38) | −0.04 (0.76) | 0.30 (<0.05) | 0.60 (<0.01) |
| Basal TLR2 | 0.50 (<0.01) | 0.83 (<0.01) | 0.05 (0.71) | −0.07 (0.58) | 0.05 (0.71) | 0.29 (<0.05) | 0.33 (<0.01) | |
| Superficial TLR2 | 0.61 (<0.01) | −0.07 (0.56) | −0.07 (0.56) | −0.01 (0.91) | 0.19 (0.13) | 0.25 (<0.05) | ||
| Total TLR2 | 0.04 (0.72) | −0.13 (0.29) | −0.01 (0.91) | 0.19 (0.13) | 0.34 (<0.01) | |||
| Basal TLR4 | 0.61 (<0.01) | 0.89 (<0.01) | 0.13 (0.32) | 0.07 (0.58) | ||||
| Superficial TLR4 | 0.72 (<0.01) | 0.23 (0.08) | −0.06 (0.62) | |||||
| Total TLR4 | 0.23 (0.08) | 0.07 (0.58) | ||||||
| FXR | 0.22 (0.08) |
Both histological and macroscopic (endoscopic) oesophagitis were divided into absent, mild and severe. Data are the correlation coefficient (p-value), calculated with 2-tailed Spearman correlation
TLR Toll-like receptor, FXR Farnesoid X receptor