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. 2021 Mar 8;479(2):285–293. doi: 10.1007/s00428-021-03066-w

Table 3.

Correlations between TLR2, TLR4 and FXR expression and oesophagitis

Basal TLR2 Superficial TLR2 Total TLR2 Basal TLR4 Superficial TLR4 Total TLR4 FXR Macroscopic oesophagitis
Histological oesophagitis 0.45 (<0.01) 0.34 (<0.01) 0.48 (<0.01) −0.04 (0.76) −0.11 (0.38) −0.04 (0.76) 0.30 (<0.05) 0.60 (<0.01)
Basal TLR2 0.50 (<0.01) 0.83 (<0.01) 0.05 (0.71) −0.07 (0.58) 0.05 (0.71) 0.29 (<0.05) 0.33 (<0.01)
Superficial TLR2 0.61 (<0.01) −0.07 (0.56) −0.07 (0.56) −0.01 (0.91) 0.19 (0.13) 0.25 (<0.05)
Total TLR2 0.04 (0.72) −0.13 (0.29) −0.01 (0.91) 0.19 (0.13) 0.34 (<0.01)
Basal TLR4 0.61 (<0.01) 0.89 (<0.01) 0.13 (0.32) 0.07 (0.58)
Superficial TLR4 0.72 (<0.01) 0.23 (0.08) −0.06 (0.62)
Total TLR4 0.23 (0.08) 0.07 (0.58)
FXR 0.22 (0.08)

Both histological and macroscopic (endoscopic) oesophagitis were divided into absent, mild and severe. Data are the correlation coefficient (p-value), calculated with 2-tailed Spearman correlation

TLR Toll-like receptor, FXR Farnesoid X receptor