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CIS patient stratification into three major groups based on KRT20 and KRT5/6 protein expression
| Major CIS group | CIS subgroup | Marker expression | Patients |
|---|---|---|---|
| - | - | - | 99 (100 %) |
| luminal | - | KRT20 positive | 46 (46 %) |
| KRT5/6 negative | |||
| null | - | KRT20 negative | 30 (30 %) |
| KRT5/6 negative | |||
| mixed | - | - | 23 (23 %) |
| 1 | KRT20 mixed | 18 | |
| KRT5/6 negative | |||
| 2 | KRT20 mixed | 3 | |
| KRT5/6 mixed | |||
| 3 | KRT20 negative | 1 | |
| KRT5/6 mixed | |||
| 4 | KRT20 mixed | 1 | |
| KRT5/6 positive |
