(A) N2A, FUS KO, and FUS re-expression (KO + WT) cells were cultured and
immunoblotting was performed using the indicated antibodies. (B) Quantification
of (A) from three independent experiments. One Way Anova was performed to
determine statistical significance. *p ≤0.05; **p≤0.01;
***p≤0.005; N.S., not significant. (C) N2A, FUS KO, and FUS re-expression
cells were cultured and harvested for RNA isolation, followed by reverse
transcription and quantitative PCR using TaqMan probes for the indicated genes.
Actin probe was used to normalize gene expression. Results from three
independent experiments are shown. Student’s t-test was
performed for individual comparisons against N2A WT cells. *, p ≤0.05;
N.S., not significant. All quantification results are shown in scatter plots
with the bar representing the median.