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HL142 attenuates the TGFβ/FAK pathway in OC cells. A, B. WB and densitometry analysis of pSMAD2 and total SMAD2 expression in OVCAR3 and OVCAR8 cells treated with 20 μM HL142 for 36h and then with 6 ng/ml TGFβ at different time points, respectively. C, D. WB and densitometry analysis of p-FAK and total FAK expression in OVCAR3 and OVCAR8 cells treated with 20 μM HL142 for 36h and then 10 μM RGD at different time points. (***p<0.001, **p<0.01, *p<0.05).
