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. 2021 Jul 29;3(3):fcab172. doi: 10.1093/braincomms/fcab172

Figure 2.

Figure 2

Changes in total oligodendrocytes, CNPase and myelin basic protein. Total oligodendrocytes (Olig2, top panel), CNPase (2′,3′-Cyclic-nucleotide 3′-phosphodiesterase, middle panel) and myelin basic protein (MBP, bottom panel) in the periventricular white matter (PVWM), lower intragyral white matter (LIWM) and upper intragyral white matter (UIWM) of the first and second parasagittal gyri, and the lateral white matter (LAWM) of sham-ischaemia (white circles, n = 9), ischaemia-vehicle (black circles, n = 8), ischaemia-Epo (red triangles, n = 8), ischaemia-hypothermia (blue triangles, n = 8), and the ischaemia-Epo-hypothermia (green diamonds, n = 8) groups at 7 days after cerebral ischaemia. Data are presented as mean ± SD. The sham control and ischaemia groups were compared using 2-Factor ANOVA with ischaemia as an independent variable and region as a repeated measure. The ischaemia groups were compared using 3-Factor ANOVA with hypothermia and rEpo as independent variables, and brain region as a repeated measure. *P < 0.05 versus sham-ischaemia; #P < 0.05 effect of rEpo; $P < 0.05 effect of hypothermia; &P < 0.05 interaction between rEpo and hypothermia.