Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 29;3(3):fcab172. doi: 10.1093/braincomms/fcab172

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Changes in astrocyte area fraction, microglia, proliferation, and apoptosis. Astrocyte area fraction [glial fibrillary acidic protein (GFAP), panel A], and numbers of microglia [ionised calcium-binding adapter molecule-1 (Iba1), panel B], proliferating cells (Ki67, panel C), and apoptotic cells (caspase3, panel D) in periventricular (PVWM) and parasagittal lower intragyral white matter (LIWM; first and second gyri combined) of the sham-ischaemia (white circles, n = 9), ischaemia-vehicle (black circles, n = 8), ischaemia-Epo (red triangles, n = 8), ischaemia-hypothermia (blue triangles, n = 8), and ischaemia-Epo-hypothermia (green diamonds, n = 8) groups at 7 days after cerebral ischaemia. Data are presented as mean ± SD. Analysis by 2-Factor ANOVA with ischaemia as an independent variable and region as repeated measure, and 3-Factor ANOVA with hypothermia and rEpo treatment as independent variables, and region treated as a repeated measure. *P < 0.05 versus sham-ischaemia; ^#P < 0.05 effect of rEpo; ^$P < 0.05 effect of hypothermia.