Table 2.
Clinical outcomes by renin tertiles
| Outcome | Tertile 1 (n = 94) | Tertile 2 (n = 93) | Tertile 3 (n = 93) | p value |
|---|---|---|---|---|
| Primary outcomes | ||||
| MAKE at hospital discharge (%) | 23 (24.5%) | 36 (38.7%) | 47 (50.5%) | 0.001 |
| Hospital mortality | 8 (8.5%) | 10 (10.8%) | 25 (26.9%) | – |
| KRT at discharge | 1 (1.1%) | 3 (3.2%) | 4 (4.3%) | – |
| Discharge eGFR ≤ 75% of baseline | 14 (14.9%) | 23 (24.7%) | 18 (19.4%) | – |
| Secondary outcomes | ||||
| Inpatient KRT (%) | 8 (8.5%) | 16 (17.2%) | 32 (34.4%) | < 0.001 |
| Duration of mechanical ventilation (days) | 0 (0–3) | 1 (0–6) | 2 (1–8) | 0.003 |
| ICU length of stay (days) | 4 (2–9) | 6 (3–11) | 8 (4–18) | 0.001 |
| Hospital length of stays (days) | 9 (5–17) | 10 (5–18) | 14 (8–22) | 0.002 |
MAKE major adverse kidney event, KRT kidney replacement therapy, eGFR estimated glomerular filtration rate, ICU intensive care unit