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. 2021 Jun 7;89(3):435–442. doi: 10.1093/neuros/nyab184

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© Congress of Neurological Surgeons 2021.

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FIGURE 2. — A, Single tissue level eQTL analysis for rs78686911 in GTEx (version 8). NES = normalized enrichment score. The m-value is the posterior probability from MetaSoft, which is the probability than an eQTL effect exists in the tested cross-tissue analysis.^23,24 An m-value < 0.01 is highly suggestive that an eQTL effect does not exist, whereas an m-value > 0.9 is highly predictive of an eQTL effect. Expression of GRIK4 across tissues available in GTEx (version 8). Gene B and exon C level expression of GRIK4 across tissues available in GTEx (gtexportal.org). TPM indicates TPM calculated from a gene model with isoforms collapsed to a single gene without additional normalization.²² The box plots represent the median and the 25th and 75th percentile. Individual points are marked as outliers if they are above/below 1.5 times the interquartile range. Data visualized were performed using gtexportal.org.

FIGURE 2. — A, Single tissue level eQTL analysis for rs78686911 in GTEx (version 8). NES = normalized enrichment score. The m-value is the posterior probability from MetaSoft, which is the probability than an eQTL effect exists in the tested cross-tissue analysis.^23,24 An m-value < 0.01 is highly suggestive that an eQTL effect does not exist, whereas an m-value > 0.9 is highly predictive of an eQTL effect. Expression of GRIK4 across tissues available in GTEx (version 8). Gene B and exon C level expression of GRIK4 across tissues available in GTEx (gtexportal.org). TPM indicates TPM calculated from a gene model with isoforms collapsed to a single gene without additional normalization.²² The box plots represent the median and the 25th and 75th percentile. Individual points are marked as outliers if they are above/below 1.5 times the interquartile range. Data visualized were performed using gtexportal.org.