Table 7.

Parameters Available at the Third Timepoint with an Independent Prognostic Value

Parameters	P	EXP(β)	95% CI
Trx-1 at first timepoint	0.003	1.001	1.001–1.002
ΔSOFA at third timepoint	0.000	1.159	1.092–1.230
CRP at second timepoint	0.000	1.008	1.004–1.013
First change of IL-6	0.006	1.203	1.054–1.373
Second change of ΔSOFA	0.001	4.994	2.000–12.469

Notes: First change index = level obtained at the second timepoint minus level obtained at the first timepoint divided by level obtained at the first timepoint; second change index = level obtained at the third timepoint minus level obtained at second timepoint divided by level obtained at the second timepoint.

Abbreviations: Trx-1, thioredoxin; CRP, C-reactive protein; IL-6, interleukin-6; ΔSOFA, sequential organ failure assessment score.