Table 2.
Multivariable Cox regression models predicting cancer-specific mortality (CSM) in 4271 upper tract urothelial carcinoma patients identified within Surveillance, Epidemiology and End Results database (2010–2016), where pathological grade was defined according to the three-tier 1973 World Health Organization (WHO) grading system
| CSM | ||
|---|---|---|
| HR (95% CI) | p-value | |
| WHO 1973 grading system, relative to G1 | ||
| G2 | 1.07 (0.55–2.08) | 0.8 |
| G3 | 1.65 (0.90–3.01) | 0.1 |
| T-stage, relative to T1 | ||
| T2 | 1.85 (1.39–2.48) | < 0.001 |
| T3 | 3.64 (2.88–4.60) | < 0.001 |
| T4 | 10.69 (8.06–14.17) | < 0.001 |
| N-stage, relative to N0 | ||
| N+ | 1.82 (1.49–2.22) | < 0.001 |
| NX | 0.79 (0.39–1.59) | 0.5 |
| Chemotherapy administration, relative to no/unknown | ||
| Yes | 0.80 (0.67–0.96) | 0.01 |
| Primary site, relative to renal pelvis | ||
| Ureter | 1.19 (1.01–1.40) | 0.03 |