Table 4.

Accuracy in cancer-specific mortality prediction at 5 years after treatment, in 4217 upper tract urothelial carcinoma patients treated with radical nephroureterectomy, identified within Surveillance Epidemiology and End Results database (2010–2016), based on multivariable Cox models: (1) without grade consideration, (2) considering the three-tier 1973 WHO grading system and (3) considering the two-tier 2004/2016 WHO grading system

	Heagerty’s C-index
(1) Model based on primary site, T-stage, N-stage and chemotherapy administration	0.74
(2) Model based on primary site, T-stage, N-stage, chemotherapy administration with the three-tier WHO 1973 grading classification system	0.76
(3) Model based on primary site, T-stage, N-stage, chemotherapy administration with the two-tier WHO 2004/2016 grading classification system	0.76

WHO World Health Organization, C-index concordance index