Table 2.

Sub-networks related to mitochondria and apoptosis

Gene set seed	Total # of neighbors	# of Measured neighbors	Median change	P-value	Activation score
Apoptosis	9457	4780	− 1.04	0.00063	7.07
Apoptotic cell clearance	310	157	1.02	0.028	− 2.36
Cell stress	1226	722	− 1.03	0.00085	1.34
Extrinsic pathway of apoptosis	221	137	1.01	0.002	− 0.24
Glucose import	1304	679	− 1.02	0.00033	0.19
Intestinal d-glucose absorption	74	36	1.05	0.0088	0.38
Intrinsic pathway of apoptosis	386	232	− 1.01	0.014	1
Oxidative stress	2889	1579	− 1.04	0.0012	1.06
Response to oxidative stress	514	323	− 1.02	0.033	0
ROS generation	2188	1170	− 1.03	0.00019	0.82
Superoxide anion generation	707	349	− 1.03	0.019	0.26

Provided in the table is the gene set seed, number of entities measured in the pathway, the median fold change, the P-value, and the activation score for the network. Transcriptome data for gut epithelial cells were obtained from Yang et al. (2020)