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Vascular lesion in aorta of Seipin−/− mice. (A) Representative H&E and Gomrori's aldehyde-fuchin staining in thoracic aorta, abdominal aorta and mesenteric artery in WT and Seipin−/− mice. (B) Electron microscopy of thoracic aorta from 6-month-old Seipin−/− and WT mice. Red arrow indicated derangement of elastic fibers in aorta. Thin red arrow showed deformed mitochondria. Green arrow indicated dilated ER. m, mitochondria; ER, endoplasmic reticulum.
