表 1.

造模24 h后三组大鼠血清细胞因子、临床表现、组织学变化的比较

Comparison of serum cytokines, clinical manifestations and histological changes in three rat groups at 24 h after modeling

Items	Rebamipide group	Colchicine group	Placebo group	F value	P value
Comparison between the rebamipide group and the colchicine group, the P value >0.05; Comparison between the rebamipide group and the placebo group, or the colchicine group and the placebo group, the P value < 0.01. Data are presented as x±s or median (minimum-maximum). IL, interleukin; TNF, tumor necrosis factor.
IL-1β/(ng/L)	27.35±7.47	27.76±5.28	41.86±5.72	14.06	< 0.001
IL-6/(ng/L)	963.53±90.22	964.08±99.31	1 575.55±167.11	65.18	< 0.001
IL-10/(ng/L)	21.68±4.83	16.20±2.49	37.96±3.76	35.60	< 0.001
TNF-α/(μg/L)	15.82±2.54	17.35±7.47	21.32±1.34	15.63	< 0.001
Clinical score	0 (0-1)	1 (0-2)	2 (1-3)		0.008
Swelling index	0.11 (0-0.20)	0.12 (0-0.16)	0.36 (0.16-0.52)		0.005
Infiltration of inflammatory cells	1 (0-2)	1 (0-2)	4 (2-4)		< 0.001