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. 2021 Aug 2;9:686303. doi: 10.3389/fchem.2021.686303

TABLE 2.

Selected PSs approved by the FDA. PS, photosensitizer, NSCLC, non-small-cell lung cancer.

Name of PS Indications and usage
Porfimer sodium • Palliation of patients with esophageal cancer
• Treatment of microinvasive endobronchial NSCLC and reduction of obstruction and palliation of symptoms in patients with completely or partially obstructing endobronchial NSCLC
• Ablation of high-grade dysplasia in Barrett’s esophagus
Aminolevulinic acid • Topical treatment of minimally to moderately thick actinic keratoses of the face or scalp, or actinic keratoses of the upper extremities
• (Oral solution) as an optical imaging agent indicated in patients with glioma as an adjunct for the visualization of malignant tissue during surgery
Methyl aminolevulinate • Treatment of thin and moderately thick, non-hyperkeratotic, non-pigmented actinic keratoses of the face and scalp in immunocompetent patients
Hexaminolevulinate • An optical imaging agent indicated for use in the cystoscopic detection of carcinoma of the bladder