Figure 5.

mtDNA localization and prediction of unique variants in iPSCs and NPCs in the three groups

(A) Thirty-four heteroplasmic variants were unique in iPSCs clones.

(B) Mitochondrial genes localization of transmitted variants in iPSCs.

(C) Predictions of unique variants in iPSCs.

(D) Thirty-one heteroplasmic variants were unique in the NPCs clones.

(E) Mitochondrial genes localization of unique variants in NPCs.

(F) Predictions of unique variants in NPCs.

syn, synonymous; nonsyn, nonsynonymous; b, benign; d, damaging.