Fig. 1.
The overall structure of nsp2. A. The nsp21-276, nsp2full-length, and nsp21-276 mutant1 (K111A/K112A/K113A) samples after size exclusion chromatography purification, respectively. B The overall structure of nsp21-276 consists of four chains in the asymmetric unit. A, B, C, D four chains are shown in pink, yellow-orange, cyan, and green, respectively. C The stereo structure of nsp21-276. The α-helices and β-sheets are colored cyan and magenta, respectively, and the three zinc atoms are shown as red, blue, and yellow spheres, respectively. The diagram of Zn2+ binding site is illustrated under the stereo structure of nsp21-276.