TABLE 1.
Baseline characteristics by region (n=1010)
| Europe | Japan | AAO | Total | p-value (exploratory) | |
| Subjects n | 779 | 115 | 116 | 1010 | |
| Sex male | 400 (51.3) | 29 (25.2) | 52 (44.8) | 481 (47.6) | <0.001 |
| Age at diagnosis years | 64.0 (52.0–73.0) | 65.0 (56.0–75.0) | 54.0 (40.3–66.0) | 63.0 (51.0–73.0) | <0.001 |
| Age category at diagnosis | |||||
| <50 years | 161 (20.7) | 20 (17.4) | 47 (40.5) | 228 (22.6) | <0.001 |
| ≥50 years and <70 years | 352 (45.2) | 46 (40.0) | 47 (40.5) | 445 (44.1) | |
| ≥70 years | 265 (34.1) | 49 (42.6) | 22 (19.0) | 336 (33.3) | |
| Not available | 1 (0.1) | 0 (0.0) | 0 (0.0) | 1 (0.1) | |
| Ethnicity # | |||||
| Caucasian/white | 749 (96.1) | 2 (1.7) | 69 (59.5) | 820 (81.2) | n/a |
| Black | 9 (1.2) | 0 (0.0) | 21 (18.1) | 30 (3.0) | |
| Asian | 6 (0.8) | 115 (100.0) | 21 (18.1) | 142 (14.1) | |
| Other | 8 (1.0) | 0 (0.0) | 3 (2.6) | 11 (1.1) | |
| Not available | 8 (1.0) | 0 (0.0) | 3 (2.6) | 11 (1.1) | |
Values are expressed as median with first and third quartiles (Q1–Q3) or n (%) unless otherwise indicated. #: totals exceed 100% since it is possible to record more than one ethnicity. “Caucasian/white” and “Asian” was recorded for one patient in Europe, two patients in Japan and one patient in America and others (AAO). Exploratory p-values are calculated for regions.