TABLE 5.
Baseline characteristics of inoperable patients, by reason for inoperability, all regions
| Technically inoperable | Comorbidities | Patient refusal | Total inoperable# | |
| Subjects n | 235 | 63 | 44 | 341 |
| Sex male | 80 (34.0) | 25 (39.7) | 16 (36.4) | 123 (36.1) |
| Age at diagnosis years | 66.0 (54.0–74.0) | 71.0 (59.3–76.8) | 71.0 (59.3–76.8) | 67.0 (56.0–76.0) |
| Age category at diagnosis | ||||
| <50 years | 42 (17.9) | 7 (11.1) | 9 (20.5) | 57 (16.8) |
| ≥50 years and <70 years | 99 (42.3) | 24 (38.1) | 11 (25.0) | 135 (39.7) |
| ≥70 years | 93 (39.7) | 32 (50.8) | 24 (54.5) | 148 (43.5) |
| Ethnicity¶ | ||||
| Caucasian/white | 167 (71.1) | 47 (74.6) | 21 (47.7) | 232 (68.0) |
| Black | 5 (2.1) | 2 (3.2) | 3 (6.8) | 11 (3.2) |
| Asian | 63 (26.8) | 14 (22.2) | 21 (47.7) | 99 (29.0) |
| Other | 1 (0.4) | 0 (0.0) | 0 (0.0) | 1 (0.3) |
| Time from onset of PH symptoms to diagnosis months | 13.0 (5.0–25.0) | 12.0 (5.5–44.5) | 16.0 (10.0–28.0) | 13.0 (6.0–28.0) |
| NYHA functional class % I/II/III/IV | 1.3/20.9/68.9/8.9 | 0.0/15.9/69.8/14.3 | 0.0/43.2/52.3/4.5 | 0.9/23.2/66.6/9.4 |
Values are expressed as median with first and third quartiles (Q1–Q3) or n (%) unless otherwise indicated. PH: pulmonary hypertension; NYHA: New York Heart Association. #: more than one reason for inoperability is possible. ¶: totals exceed 100% since it is possible to record more than one ethnicity. “Caucasian/white” and “Asian” was recorded for one patient in Europe, two patients in Japan and one patient in America and others.