Table 1.

Overview of Studies

Overview				Demographics
Study	Number of Knees	Patients per Study Arm	Population	Country	Mean Age	Male	Female
Park et al., 201314	n = 120	n = 40 for each arm	Patients with degenerative OA (K-L 2 or 3)	Korea	63.59	21	99
Im et al., 200915	n = 89	n = 45 for sonographically guided, n = 44 for blind injection	Patients with radiographically confirmed knee OA (K-L 2 or 3)	Korea	60.10	24	65
Jang et al., 201316	n = 126	n = 44 for ultrasound, n = 41 for out of plane, n = 41 for blind injection	Patients with radiographically confirmed knee OA (K-L 2 or 3)	Korea	61.55	27	99
Park et al., 201217	n = 99	n = 50 for ultrasound, n = 49 for blind injection	Patients with radiographically confirmed knee OA	Korea	60.00	28	72
Wiler et al., 201018	n = 66	n = 39 for ultrasound, n = 27 for landmark	Patients requiring knee arthrocentesis	USA	79.75	43	23
Sibbitt et al., 201219	n = 64	n = 22 for anatomic-guided, n = 22 for ultrasound-guided with mechanical aspirating syringe, n = 20 for ultrasound-guided with automatic aspirating syringe	Patients with arthritis (K-L 1-3) and persistent pain in involved joint	USA	N/A	N/A	N/A
Hashemi et al., 201620	n = 220	n = 100 for ultrasound, n = 123 for blind injection	Patients with osteoarthritis diagnosis based on American College of Rheumatology definition	Iran	64.07	60	163
Cunnington et al., 201021	n = 68	n = 35 for ultrasound, n = 33 for clinical examination–guided	Patients with a diagnosis of inflammatory arthritis	USA	58.15	N/A	N/A
Toda et al., 200822	n = 50	n = 50 for modified Waddell, n = 50 for anteromedial approach, and n = 50 for lateral patellar approach	Patients with medial compartment OA knee	USA	66.10	8	42
Wada et al., 201823	n = 150	n = 75 for isometric quadriceps method, n = 75 for nonactivated quadriceps method	Patients with radiographically confirmed knee OA	Japan	73.55	75	75
Chernchujit et al., 201924	n = 132	n = 66 for modified anterolateral, n = 66 for superolateral	Patients with symptomatic OA without effusion	Thailand	N/A	N/A	N/A
Wind et al., 200425	n = 131	n = 44 for superolateral, n = 43 for superomedial, n = 44 for lateral joint	Patients presenting for routine knee arthroscopy	USA	43.00	N/A	N/A

K-L, Kellgren-Lawrence; OA, osteoarthritis; N/A, not available.