Table 1.
17 major GO Biological Process categories for the 160 conserved proteins with phosphosites showing more than 2‐fold change within 40 min of Torin1 addition.
| GO term | Frequency | Gene names (Essential genes in bold) |
|---|---|---|
| Signalling (GO:0023052) | 37 (5) | amk2, atg1, bzz1, cek1, far11, gtr2, igo1, iml1, inp53, kcs1, mor2, orb6, pab1, par1, pik1, pom1, pom2, ppk19, ppk25, ppk30, ras1, rga3, rgf1, rnc1, rng2, sat1, sck1, sck2, sea2, sea3, sec73, SPAC824.09c, SPBC16E9.02c, stm1, syt22, win1, wis1 |
| Vesicle‐Mediated Transport (GO:0016192) | 33 (10) | bzz1, cdc15, ede1, gga21, glo3, gyp1, irs4, mpd2, mvp1, nxt3, orb6, osh2, pan1, pep12, pob1, ppk19, sat1, sec16, sec2, sec27, sec31, sec5, sec73, sec9, SPAC824.09c, SPCC622.14, sst4, syb1, syt22, trs130, vps17, vti1, wdr44 |
| Cytoplasmic Translation (GO:0002181) | 15 (10) | erf1, hrs1, rpl8,rps101, rps601, rps602, slh1, SPAC29E6.06c , sum2, sum3, sup35, tif212, tif225, tif303, tif471 |
| Ribosome Biogenesis (GO:0042254) | 15 (4) | enp1, noc12, nup124, nup146, nup40, pxr1, rei1, rpl8, rps101, rps601, rps602, SPBC16H5.08c, SPBC4.02c, tif471, tif6 |
| Actin Cytoskeleton Organization (GO:0030036) | 13 (2) | bud6, bzz1, cdc15, ede1, imp2, myp2, orb6, pan1, pom1, ppk30, pxl1, rng2, tea4 |
| Autophagy (GO:0006914) | 13 (1) | atg1, atg11, atg13, atg3, atg9, gtr2, iml1, irs4, nxt3, osh2, ppk19, sec16, ubx3 |
| Establishment or Maintenance of Cell Polarity (GO:0007163) | 13 (2) | alp14, bud6, cdc15, mor2, mto1, orb6, osh2, pom1, ras1, syt22, tea1, tea3, tea4 |
| Chromatin Organization (GO:0006325) | 12 (2) | bdf2, eaf6, eaf7, hta2, nap1, nap2, pst3, set2, sgf29, shf1, SPBC4.02c, taf12 |
| Membrane Organization (GO:0061024) | 12 (6) | cdc15, glo3, mvp1, ned1, pep12, sec16, sec31, sec9, syb1, ubx3, vps17, vti1 |
| Protein‐Containing Complex Assembly (GO:0065003) | 12 (6) | alp14, brr2, bud6, mto1, nap1, nap2, rng2, sec16, taf12, tif212, tif303, tif6 |
| Transcription, DNA‐Templated (GO:0006351) | 12 (6) | eaf7, hsf1, maf1, nup40, pst3, rpc37, set2, sfp1, sgf29, taf12, tfa1, tfg1 |
| Nucleocytoplasmic Transport (GO:0006913) | 11 (2) | kap123, ned1, npp106, nup124, nup146, nup40, nup61, ras1, rei1, SPBC16H5.08c, tif6 |
| mRNA Metabolic Process (GO:0016071) | 9 (1) | brr2, ccr4, cip1, cip2, not2, not3, rnc1, sts5, vts1 |
| DNA Repair (GO:0006281) | 8 (2) | eaf6, eaf7, hta1, hta2, pms1, pst3, rad21, ung1 |
| Mitotic Cell Cycle Phase Transition (GO:0044772) | 8 (0) | cek1, igo1, pab1, par1, pom1, rad25, sck2, wis1 |
| Mitotic Cytokinesis (GO:0000281) | 8 (1) | cdc15, igo1, imp2, myp2, pom1, pom2, pxl1, rng2 |
| Transmembrane Transport (GO:0055085) | 8 (1) | abc2, avt3, can1, pmc1, sbh1, sec62, SPCC1672.11c, stm1 |
| Uncategorised | 17 (0) | ada1, dml1, gde1, gpd1, izh3, knk1, nrp1, ntp1, nvj2, pcc1, pcy1, scw1, SPAC22A12.14c, SPBC30D10.05c, tcb2, tmf1, ubp7 |