Table 3.
Estimates of increasing rate of viral load from the time of diagnosis to cART initiation
| N | Increase rate of viral load (log10copies/ml/year) | Increase rate of viral load (log10copies/ml/year) | ||||
|---|---|---|---|---|---|---|
| Mean (95%CI) | P value | P value | Adjusted mean (95%CI)* | P value | ||
| CD4 200–350 | ||||||
| CRF55_01B | 29 | 3.5 (1.5, 5.5) | Ref | Ref | Ref | |
| CRF01_AE | 33 | 1.9 (0.9, 2.9) | 0.150 | Ref | − 1.4 (− 3.2, 0.4) | 0.136 |
| CRF07_BC | 27 | 0.9 (0.5, 1.3) | < 0.05 | < 0.05 | − 2.6 (− 4.5, − 0.7) | < 0.05 |
| CD4 ≥ 350 | ||||||
| CRF55_01B | 28 | 0.9 (0.6, 1.2) | Ref | Ref | Ref | |
| CRF01_AE | 21 | 1.4 (0.8, 2.0) | 0.400 | Ref | 0.2 (− 0.2, 0.7) | 0.345 |
| CRF07_BC | 28 | 0.7 (0.5, 0.9) | 0.606 | 0.215 | − 0.1 (− 0.5, 0.4) | 0.769 |
| All ≥ 200 | ||||||
| CRF55_01B | 65 | 2.0 (1.1, 2.9) | Ref | Ref | Ref | |
| CRF01_AE | 65 | 1.4 (0.8, 2.0) | 0.324 | Ref | − 0.5 (− 1.5, 0.4) | 0.250 |
| CRF07_BC | 69 | 0.7 (0.5, 0.9) | < 0.05 | < 0.05 | − 1.2 (− 2.1, − 0.3) | < 0.01 |
* The Adjusted mean was estimated with adjustment of age at HIV diagnosis, ethnicity, marital status, and year of HIV diagnosis