. 2021 Aug 5;24(4):702. doi: 10.3892/mmr.2021.12341

Table VI.

Types of differentially expressed gene.

Family	Gene
Enzyme	ARG1^a, SMPD2^a, COMT^a, SNCA^b, PPIA^b, PLG^b, DGKG ^a, RET^a, KALRN^a, DUSP9^a, HPN^a
Cytokines	SPP1^a
Growth factor	NTF3^a, BDNF^a
Transcription factor	NEUROD6^a, TFAP2B^b
Ion channel	HCN1^a, GRIN2A^a, SCN5A^b, KCNJ3^a, KCNS3^a, TRPC4^a, KCNA5^b
Transmembrane and nuclear receptors	KIT^a, NR4A3^a
Other	BAIAP2L1^a, COL1A1^b, HSPA2^a, PDLIM5^b, TAC1^b, PENK^b, NPTX1^a, PKP2^a, RSPO2^a, SHOC2^b, HOMER3^a, CNKSR2^a

Upregulated.

Downregulated. ARG1, arginase 1; SMPD2, sphingomyelin phosphodiesterase 2; COMT, catechol-o-methyltransferase; SNCA, synuclein alpha; PPIA, peptidylprolyl isomerase A; PLG, plasminogen; DGKG, diacylglycerol kinase gamma; RET, ret proto-oncogene; KALRN, kalirin rhoGEF kinase; DUSP9, dual specificity phosphatase 9; HPN, hepsin; SPP1, secreted phosphoprotein 1; NTF3, neurotrophin 3; BDNF, brain-derived neurotrophic factor; NEUROD6, neuronal differentiation 6; TFAP2B, transcription factor AP-2β; HCN1, hyperpolarization activated cyclic nucleotide gated potassium channel 1; GRIN2A, glutamate ionotropic receptor NMDA type subunit 2A; SCN5A, sodium voltage-gated channel α subunit 5; KCNJ3, potassium inwardly rectifying channel subfamily J member 3; KCNS3, potassium voltage-gated channel modifier subfamily S member 3; TRPC4, transient receptor potential cation channel subfamily C member 4; KCNA5, potassium voltage-gated channel subfamily A member 5; KIT, kit proto-oncogene; NR4A3, nuclear receptor subfamily 4 group A member 3; BAIAP2L1, BAR/IMD domain containing adaptor protein 2 like 1; COL1A1, Collagen type I α1 chain; HSPA2, heat shock protein family A (Hsp70) member 2; PDLIM5, PDZ and LIM domain 5; TAC1, tachykinin precursor 1; PENK, proenkephalin; NPTX1, neuronal pentraxin 1; PKP2, plakophilin 2; RSPO2, r-spondin 2; SHOC2, SHOC2 leucine rich repeat scaffold protein; HOMER3, homer scaffold protein 3; CNKSR2, connector enhancer of kinase suppressor of ras 2.