TABLE 4.
Sensitivity and specificity of four methods for examination results of sputum samples.
| Methodsa |
Sputum samplesb
|
Sensitivity (%) | Specificity (%) | PPVc (%) | NPVd (%) | |
| TB cases (N = 84) | Non-TB cases (N = 24) | |||||
| AFB smear | ||||||
| Positive | 39 | 0 | 47.56 | 100 | 100 | 34.78 |
| Negative | 45 | 24 | ||||
| L-J culture | ||||||
| Positive | 73 | 0 | 86.90 | 100 | 100 | 68.57 |
| Negative | 11 | 24 | ||||
| Multiplex PCR | ||||||
| Positive | 79 | 0 | 94.05 | 100 | 100 | 82.76 |
| Negative | 5 | 24 | ||||
| mLAMP-LFB | ||||||
| Positive | 82 | 0 | 97.62 | 100 | 100 | 92.31 |
| Negative | 2 | 24 | ||||
aAFB, acid-fast bacilli; L-J, Lowenstein–Jensen medium; PCR, polymerase chain reaction; mLAMP, multiplex loop-mediated isothermal amplification; LFB, lateral flow biosensor.
bTB, tuberculosis.
cPPV, positive predictive value.
dNPV, negative predictive value.