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. 2021 Aug 2;9:696640. doi: 10.3389/fcell.2021.696640

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Copyright © 2021 Hayes and Melrose.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic depiction of the modular structures of diverse cell surface molecules expressed by neural cells that bind CS-proteoglycans. The fibronectin-III and Ig repeat transmembrane protein LAR (Leukocyte common antigen-related receptor protein tyrosine phosphatase (A) and homologous contactin-1 (CNTN-1) (B) Murine paired immunoglobulin receptor B (PirB) and its human ortholog leukocyte immunoglobulin-like receptor B2 (LILRB2) (C), neural cell adhesion molecule (NrCAM) (D). The ephrin receptor (E), Nogo and its co-receptors (F), semaphorins 3A (G), 5A (H) and the neuropilin (I) and neuroplexin receptors (J).