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. 2021 Apr 21;78(14):1294–1308. doi: 10.1093/ajhp/zxab160

Table 2.

Factors Driving Growth of Pharmaceutical Expenditures in Clinics and Nonfederal Hospitals in 2020, by Product Categorya

Product Category Clinics Nonfederal Hospitals
Total Percent Growth Percent Growth Due to Factor Total Percent Growth Percent Growth Due to Factor
New Products Price Volume and Mix New Products Price Volume and Mix
All products 8.1 2.3 –1.5 7.3 –4.6 4.6 0.5 –9.7
 Injectables 7.6 2.8 –1.6 6.4 –4.9 5.7 0.9 –11.5
  Branded 8.4 2.8 –1.7 7.3 –6.0 7.2 1.3 –14.5
  Generic –2.7 4.0 –4.2 –2.5 –5.0 2.4 –3.8 –3.6
  Branded generic –0.1 0.5 1.4 –2.0 2.5 0.2 3.9 –1.6
 Noninjectables 10.9 0.9 –1.1 11.1 –3.7 1.0 –0.9 –3.8
  Branded 13.9 0.5 –0.1 13.5 0.6 0.2 0.2 0.2
  Generic –5.8 4.4 –10.8 0.6 –5.1 3.7 –3.3 –5.5
  Branded generic 5.3 0.2 2.8 2.3 –12.6 0.1 –1.4 –11.3

aTotal growth comprised growth attributable to 3 factors: (1) new products (products that were not on the market in the previous year), primarily newly approved and marketed agents; (2) price (changes in the unit cost of drugs that were on the market in the previous year); and (3) volume and mix (changes in volume of utilization of existing products or changes in utilization patterns [eg, a shift from one product to another, as when prescribing moves from branded to generic products]).