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. 2021 Apr 21;78(14):1294–1308. doi: 10.1093/ajhp/zxab160

Table 6.

Top 25 Therapeutic Drug Category by Expenditures in Nonfederal Hospitals in 2020

Drug Category 2020 Expenditures
($ Thousands)
Percent of Total 2020 Expenditures Percent Change from 2019
Antineoplastic agents 6,679,358 19.6 –15.7
Hemostatic modifiers 2,772,502 8.1 –5.1
Immunologic agents 2,652,874 7.8 6.7
Antiviral drugs 2,430,234 7.1 78.3
Biologicals 2,087,790 6.1 –8.7
Antiinfectives, systemica 1,555,780 4.6 –15.9
Miscellaneous 1,437,613 4.2 –1.1
Hospital solutions 1,430,023 4.2 –14.4
Blood factors 1,390,327 4.1 –15.7
Anesthetics 1,228,846 3.6 11.4
Hormones 1,208,486 3.5 16.7
Diagnostic aids 1,184,344 3.5 –11.5
Respiratory therapy agents 1,068,329 3.1 –1.7
Gastrointestinal agents 1,041,044 3.1 –15.4
Antiarthritics 813,810 2.4 8.7
Musculoskeletal agents 719,980 2.1 8.1
Neurological disorder drugs 704,557 2.1 –26.2
Psychotherapeutics 686,276 2.0 0.9
Analgesics 620,160 1.8 –13.3
Diabetes therapies 520,603 1.5 11.5
Cardiac agents 418,946 1.2 –7.8
Vascular agents 414,665 1.2 –15.0
Antifungal agents 347,311 1.0 –8.3
Enzymes 343,941 1.0 –3.0
Ophthalmic agents 327,178 1.0 –5.5

aIncludes mostly antibacterials along with some antiparasitic agents, with the latter having minimal impact in terms of expenditures.