Table 4.
Effect of tsumire intake on blood biochemical parameters in Sprague–Dawley rats after 84 d of administration
| ‘0’ d administration (n 8) | 84 d administration (n 8) | ||
|---|---|---|---|
| Group I (without tsumire) | Group II (with tsumire) | ||
| TP (g/dl) | 6·36 ± 0·05 | 6·55 ± 0·09 | 6·40 ± 0·13 |
| ALB (g/dl) | 4·61 ± 0·03 | 4·38 ± 0·04 | 4·15 ± 0·09 |
| A/G (−) | 2·65 ± 0·06 | 2·03 ± 0·07 | 1·85 ± 0·05 |
| BUN (mg/dl) | 19·73 ± 1·34 | 19·40 ± 0·66 | 17·91 ± 0·31 |
| CRE (mg/dl) | 0·23 ± 0·01 | 0·36 ± 0·01 | 0·36 ± 0·02 |
| Na (mEq/l) | 141·63 ± 0·17 | 142·13 ± 0·37 | 140·13 ± 0·41** |
| K (mEq/l) | 5·03 ± 0·09 | 4·48 ± 0·03 | 4·65 ± 0·12 |
| Cl (mEq/l) | 100·88 ± 0·45 | 101·13 ± 0·33 | 101·00 ± 0·25 |
| Ca (mg/dl) | 11·46 ± 0·10 | 10·64 ± 0·08 | 10·38 ± 0·06* |
| IP (mg/dl) | 8·74 ± 0·24 | 5·70 ± 0·08 | 6·20 ± 0·15* |
| Fe (μg/dl) | 208·25 ± 9·20 | 162·50 ± 5·33 | 156·00 ± 9·12 |
| AST (IU/l) | 118·88 ± 10·26 | 104·50 ± 3·36 | 76·25 ± 2·75** |
| ALT (IU/l) | 43·50 ± 2·11 | 30·13 ± 1·39 | 26·13 ± 1·05* |
| ALP (IU/l) | 1865·75 ± 220·78 | 499·75 ± 56·04 | 396·50 ± 32·61 |
| LDH (IU/l) | 1021·13 ± 165·60 | 1521·25 ± 72·75 | 952·50 ± 131·97** |
| LAP (IU/l) | 60·38 ± 1·67 | 55·00 ± 1·51 | 49·63 ± 1·07* |
| AMY (IU/l) | 2577·75 ± 123·15 | 2065·50 ± 76·41 | 1839·38 ± 57·05* |
| γ-GT (IU/l) | <3·00 | <3·00 | <3·00 |
| ChE (IU/l) | 13·13 ± 1·02 | 9·75 ± 0·34 | 6·63 ± 0·43** |
| T-CHO (mg/dl) | 96·13 ± 4·27 | 95·00 ± 4·07 | 87·13 ± 6·59 |
| F-CHO (mg/dl) | 20·63 ± 1·09 | 15·75 ± 0·86 | 16·38 ± 1·53 |
| E-CHO (mg/dl) | 75·50 ± 3·23 | 79·25 ± 3·30 | 70·75 ± 5·12 |
| E/T (%) | 78·63 ± 0·30 | 83·38 ± 0·39 | 81·25 ± 0·55* |
| TAG (mg/dl) | 113·38 ± 7·96 | 133·50 ± 11·95 | 135·25 ± 26·40 |
| LDL-C (mg/dl) | 11·63 ± 0·73 | 9·63 ± 0·56 | 8·13 ± 0·67 |
| HDL-C (mg/dl) | 40·25 ± 1·20 | 32·75 ± 0·82 | 30·38 ± 1·75 |
| AIPa (–) | 0·08 ± 0·03 | 0·16 ± 0·05 | 0·23 ± 0·09 |
| GLU (mg/dl) | 135·00 ± 1·59 | 158·63 ± 7·60 | 230·13 ± 14·25** |
| T-BIL (mg/dl) | 0·04 ± 0·00 | 0·06 ± 0·00 | 0·08 ± 0·01 |
| D-BIL (mg/dl) | 0·01 ± 0·00 | 0·03 ± 0·00 | 0·03 ± 0·00 |
| I-BIL (mg/dl) | 0·02 ± 0·00 | 0·04 ± 0·00 | 0·05 ± 0·01 |
| TBA (μmol/l) | 21·63 ± 1·85 | 13·88 ± 2·25 | 11·38 ± 2·13 |
TP, total proteins; ALB, albumin; BUN, blood urea nitrogen; CRE, creatinine; Na, sodium; K, potassium; Cl, chloride; Ca, calcium; IP, inorganic phosphorus; Fe, iron; AST, aspartate aminotransferase; ALT, alanine transaminase; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; LAP, leucine aminopeptidase; AMY, amylase; γ-GT, γ-glutamyl transpeptidase; ChE, cholinesterase; T-CHO, total cholesterol; F-CHO, free cholesterol; E-CHO, esterified cholesterol; TAG, triacylglycerols; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; AIP, atherogenic index of plasma; GLU, glucose; T-BIL, total bilirubin; D-BIL, direct bilirubin; I-BIL, indirect bilirubin; TBA, total bile acids.
Results are expressed as mean ± standard error. Statistical significance is evaluated by Student's t-test.
P < 0·01 v. Group I, *P < 0·05 v. Group I.
AIP: log (TAG/HDL-C) with TAG (mg/dl/88·57) and HDL-C (mg/dl/38·67) expressed in mmol/l (15).