Table 1. Inhibition of Human Isolated 5-LOX and 5-LOX Product Formation in Activated PMNL by Garcinoic Acid-Derived Compounds (12a–25)e.
IC50 values (μM).
Residual activities (% control) at 1 μM compound concentration.
Residual activities (% control) at 3 μM compound concentration.
Highlighted data (gray) are from Pein et al.6 n.d., not determined.
All values are given as mean ± standard error of the mean (SEM) of single determinations obtained in 3–6 independent experiments.