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. 2021 Jul 19;64(15):11496–11526. doi: 10.1021/acs.jmedchem.1c00806

Table 2. Inhibition of Human Isolated 5-LOX and 5-LOX Product Formation in Activated PMNL by Amplexichromanol-Derived Compounds (26–48)e.

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a

IC50 values (μM).

b

Residual activities (% control) at 1 μM compound concentration.

c

Residual activities (% control) at 3 μM compound concentration.

d

Highlighted data (gray) are from Pein et al.6 n.d., not determined.

e

All values are given as mean ± SEM of single determinations obtained in 3–4 independent experiments.