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. 2021 Jul 15;64(15):10849–10877. doi: 10.1021/acs.jmedchem.0c02274

Table 1. CAMKK2 Enzyme Inhibition Data for Compounds with 3- and 3,5-Substituted Fused 5,6-Ring Systemsa.

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a

R = ortho-cyclopentyl benzoic acid moiety; PoC (percent of control = percent of enzyme activity remaining, when compared with the control); IC50 (half-maximal inhibitory concentration); NG (not generated); IC50 values were generated in an 8-point full dose response assay.