Table 2. CAMKK2 Enzyme Inhibition Data for Compounds with 2- and 2,4-Substituted Fused 6,5-Ring Systemsa.
R = ortho-cyclopentyl benzoic acid moiety; PoC (percent of control = percent of enzyme activity remaining, when compared with control); IC50 (half-maximal inhibitory concentration); IC50 values were generated in an 8-point full dose response assay.