TABLE 2.

Effects of i.c.v. kisspeptin injection (3 nmol) on metabolic outcomes

Comparison	Parameter	Treatment	Time	Interaction
Baseline vs vehicle i.c.v.	Cumulative food intake	F1,8 = 0.9580 P = 0.356	F95,760 = 206.5 P < 0.0001	F95,760 = 1.337 P = 0.023
	Cumulative water intake	F1,8 = 2.306 P = 0.167	F95,760 = 132.6 P < 0.0001	F95,760 = 3.595 P < 0.0001
	Locomotor activity	F1,8 = 4.798 P = 0.060	F95,760 = 6.120 P < 0.0001	F95,760 = 1.257 P = 0.058
	RER	F1,8 = 1.189 P = 0.307	F95,760 = 13.00 P < 0.0001	F95,760 = 1.571 P = 0.0008
	Heat	F1,8 = 0.5588 P = 0.476	F95,760 = 6.942 P < 0.0001	F95,760 = 0.9260 P = 0.675
Baseline vs Kp10 i.c.v.	Cumulative food intake	F1,8  = 13.84 P = 0.006	F95,760 = 264.5 P < 0.0001	F95,760 = 9.056 P < 0.0001
	Cumulative water intake	F1,8 = 1.038 P = 0.338	F95,760 = 259.7 P < 0.0001	F95,760 = 0.8811 P =.779
	Locomotor activity	F1,8  = 13.04 P = 0.007	F95,760  = 6.759 P < 0.0001	F95,760 = 1.675 P = 0.0001
	RER	F1,8  = 13.48 P = 0.006	F95,760 = 12.87 P < 0.0001	F95,760 = 3.121 P < 0.0001
	Heat	F1,8 = 4.479 P =.067	F95,760 = 6.288 P < 0.0001	F95,760 = 1.779 P < 0.0001
Vehicle i.c.v. vs Kp10 i.c.v.	Cumulative food intake	F1,8  = 30.19 P =.0006	F95,760  = 117.9 P < 0.0001	F95,760 = 12.39 P < 0.0001
	Cumulative water intake	F1,8 = 1.105 P = 0.324	F95,760  = 139.8 P < 0.0001	F95,760 = 0.5516 P = 0.999
	Locomotor activity	F1,8 = 0.8578 P = 0.382	F95,760  = 6.409 P < 0.0001	F95,760 = 0.6796 P = 0.991
	RER	F1,8  = 25.42 P = 0.001	F95,760  = 12.78 P < 0.0001	F95,760 = 1.169 P = 0.141
	Heat	F1,8 = 0.04709 P = 0.834	F95,760  = 5.061 P < 0.0001	F95,760 = 0.8237 P = 0.883

Kp, kisspeptin; RER, respiratory exchange ratio.

Significant values are indicated in bold.